I had always assumed that this process required a circulating immersion heater (like sous-vide cooking) precisely for that reason. Those can keep a water bath, as long as the volume of water is not too large, within 0.1 C or so of the target temperature. I had never thought an oven would be well regulated enough until I read Ellen's post yesterday. That must be a very well controlled oven indeed. Alberto, how does your group control the temperature in your research? On 5/9/2013 8:00 AM, David Pilling wrote: > Hi, > > In message <BAY156-W248FECDB93ECAC113B9B1FAEA40@phx.gbl>, Alberto > Castillo <ezeizabotgard@hotmail.com> writes >> recover. The reason is evident: to reach 46 C at the core the outer >> portion must be almost boiled. > The laws of thermodynamics beg to differ. If your bulbs are exposed to a > constant 46C for long enough (above there is mention of 2 hours) the > temperature at the centre will be the same as outside. > >